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Anti-C5 Antibody (CAT#: MOM-18008)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human C5 Antibody MOM-18008 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) Antibody is bind to Human C5, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • C5
  • Type
  • Humanized (from mouse) IgG2 / G4 - kappa
  • Immunogen
  • Human C5 protein emulsified with complete Fraud's adjuvant
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, WB and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Protein Construction
  • Immunoglobulin, anti-(human complement C5 a-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide with human-mouse monoclonal 5G1.1 light chain, dimer
  • Predicted N terminal
  • H chain: MADLQMT; L Chain: MGIQGGS
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190 kDa glycoprotein consisting of a disulphide linked alpha-chain (111 kDa) and beta-chain (75 kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha chain).
  • Function
  • C5a anaphylatoxin chemotactic receptor binding; chemokine activity; endopeptidase inhibitor activity; receptor binding;
  • Synonyms
  • C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;

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